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Article

Common polymorphisms in the prostaglandin pathway genes and their association with breast cancer susceptibility and survival.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Mar 2009

Abraham Jean E, Harrington Patricia, Driver Kristy E, Tyrer Jonathan, Easton Douglas F, Dunning Alison M, Pharoah Paul D P

Abstract excerpt

PURPOSE: There is evidence that genetic variation in the prostaglandin pathway affects cancer susceptibility and progression. Conflicting data from several studies exist for the association of PTGS2 (cyclooxygenase 2) polymorphisms with breast cancer risk. We investigated associations between common germ-line variations in seven genes in the prostaglandin pathway and breast cancer susceptibility and survival...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19276290
DOI: 10.1158/1078-0432.CCR-08-0716

Genes

PTGS2
PTGDS
PTGES
PTGIS
PTGS1
TBXAS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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