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Article

Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein.

Nature neuroscience - 30 Oct 2011

Bhogal Balpreet, Jepson James E, Savva Yiannis A, Pepper Anita S-R, Reenan Robert A, Jongens Thomas A

Abstract excerpt

Loss of FMR1 gene function results in fragile X syndrome, the most common heritable form of intellectual disability. The protein encoded by this locus (FMRP) is an RNA-binding protein that is thought to primarily act as a translational regulator; however, recent studies have implicated FMRP in other mechanisms of gene regulation. We found that the Drosophila fragile X homolog (dFMR1) biochemically interacted with...

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Identifiers

PMID: 22037499
DOI: 10.1038/nn.2950
PMCID: PMC3225737

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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