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Article

The Drosophila fragile X mental retardation protein controls actin dynamics by directly regulating profilin in the brain.

Current biology : CB - 21 Jun 2005

Reeve Simon P, Bassetto Laura, Genova Ginka K, Kleyner Yelena, Leyssen Maarten, Jackson F Rob, Hassan Bassem A

Abstract excerpt

Loss of Fragile X mental retardation protein (FMRP) function causes the highly prevalent Fragile X syndrome [1 and 2]. Identifying targets for the RNA binding FMRP is a major challenge and an important goal of research into the pathology of the disease. Perturbations in neuronal development and c...

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Identifiers

PMID: 15964283
DOI: 10.1016/j.cub.2005.05.050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15964283-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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