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Article

Longitudinal evaluation of FGF23 changes and mineral metabolism abnormalities in a mouse model of chronic kidney disease.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jan 2012

Stubbs Jason R, He Nan, Idiculla Arun, Gillihan Ryan, Liu Shiguang, David Valentin, Hong Yan, Quarles L Darryl

Abstract excerpt

Fibroblast growth factor 23 (FGF23) is a phosphaturic and vitamin D-regulatory hormone of putative bone origin that is elevated in patients with chronic kidney disease (CKD). The mechanisms responsible for elevations of FGF23 and its role in the pathogenesis of chronic kidney disease-mineral bone disorder (CKD-MBD) remain uncertain. We investigated the association between FGF23 serum levels and kidney disease...

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Source

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Identifiers

PMID: 22031097
DOI: 10.1002/jbmr.516
PMCID: PMC3439562

Genes

FGF23
PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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