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Article

Age- and islet autoimmunity-associated differences in amino acid and lipid metabolites in children at risk for type 1 diabetes.

Diabetes - 1 Nov 2011

Pflueger Maren, Seppänen-Laakso Tuulikki, Suortti Tapani, Hyötyläinen Tuulia, Achenbach Peter, Bonifacio Ezio, Orešič Matej, Ziegler Anette-G

Abstract excerpt

OBJECTIVE: Islet autoimmunity precedes type 1 diabetes and often initiates in childhood. Phenotypic variation in islet autoimmunity relative to the age of its development suggests heterogeneous mechanisms of autoimmune activation. To support this notion, we examined whether serum metabolite profiles differ between children with respect to islet autoantibody status and the age of islet autoantibody development....

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Identifiers

PMID: 22025777
DOI: 10.2337/db10-1652
PMCID: PMC3198092

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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