Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Elevations in blood glucose before and after the appearance of islet autoantibodies in children.

The Journal of clinical investigation - 17 Oct 2022

Warncke Katharina, Weiss Andreas, Achenbach Peter, von dem Berge Thekla, Berner Reinhard, Casteels Kristina, Groele Lidia, Hatzikotoulas Konstantinos, Hommel Angela, Kordonouri Olga, Elding Larsson Helena, Lundgren Markus, Marcus Benjamin A, Snape Matthew D, Szypowska Agnieszka, Todd John A, Bonifacio Ezio, Ziegler Anette-G

Abstract excerpt

The etiology of type 1 diabetes has polygenic and environmental determinants that lead to autoimmune responses against pancreatic β cells and promote β cell death. The autoimmunity is considered silent without metabolic consequences until late preclinical stages,and it remains unknown how early in the disease process the pancreatic β cell is compromised. To address this, we investigated preprandial nonfasting and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to Autoimmunity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood Glucose

Share to Child, Preschool

Share to Diabetes Mellitus, Type 1

Share to Genetic Predisposition to Disease

Share to Islets of Langerhans

Source

Open in PubMed Open full text

Identifiers

PMID: 36250461
DOI: 10.1172/JCI162123
PMCID: PMC9566912

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Elevations in blood glucose before and after the appearance of islet autoantibodies in children.PMID 36250461Read ↗

Age-related islet autoantibody incidence in offspring of patients with type 1 diabetes.Semantic proximity Read ↗

Early Autoantibody Responses in Prediabetes Are IgG1 Dominated and Suggest Antigen-Specific RegulationSemantic proximity Read ↗

The first signs of beta-cell autoimmunity appear in infancy in genetically susceptible children from the general population: the Finnish Type 1 Diabetes Prediction and Prevention Study.Semantic proximity Read ↗

The Multifactorial Progression from the Islet Autoimmunity to Type 1 Diabetes in Children.Semantic proximity Read ↗

Islet autoantibody phenotypes and incidence in children at increased risk for type 1 diabetes.Semantic proximity Read ↗

Patterns of β-cell autoantibody appearance and genetic associations during the first years of life.Semantic proximity Read ↗

Oral insulin immunotherapy in children at risk for type 1 diabetes in a randomized trialSemantic proximity Read ↗

The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study.Semantic proximity Read ↗

Prediabetes in children: natural history, diagnosis, and preventive strategies.Semantic proximity Read ↗

Sugar intake is associated with progression from islet autoimmunity to type 1 diabetes: the Diabetes Autoimmunity Study in the Young.Semantic proximity Read ↗

Brief communication: early appearance of islet autoantibodies predicts childhood type 1 diabetes in offspring of diabetic parents.Semantic proximity Read ↗

Increasing plasma glucose before the development of type 1 diabetes-the TRIGR study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.