Article
Cord serum lipidome in prediction of islet autoimmunity and type 1 diabetes.
Diabetes - 1 Sept 2013
Oresic Matej, Gopalacharyulu Peddinti, Mykkänen Juha, Lietzen Niina, Mäkinen Marjaana, Nygren Heli, Simell Satu, Simell Ville, Hyöty Heikki, Veijola Riitta, Ilonen Jorma, Sysi-Aho Marko, Knip Mikael, Hyötyläinen Tuulia, Simell Olli
Abstract excerpt
Previous studies show that children who later progress to type 1 diabetes (T1D) have decreased preautoimmune concentrations of multiple phospholipids as compared with nonprogressors. It is still unclear whether these changes associate with development of β-cell autoimmunity or specifically with clinical T1D. Here, we studied umbilical cord serum lipidome in infants who later developed T1D (N = 33); infants who...
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