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Article

The dCMP transferase activity of yeast Rev1 is biologically relevant during the bypass of endogenously generated AP sites.

DNA repair - 10 Dec 2011

Kim Nayun, Mudrak Sarah V, Jinks-Robertson Sue

Abstract excerpt

The bypass of AP sites in yeast requires the Rev1 protein in addition to the Pol ζ translesion synthesis DNA polymerase. Although Rev1 was originally characterized biochemically as a dCMP transferase during AP-site bypass, the relevance of this activity in vivo is unclear. The current study uses highly sensitive frameshift- and nonsense-reversion assays to monitor the bypass of AP sites created when uracil is...

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Identifiers

PMID: 22024240
DOI: 10.1016/j.dnarep.2011.09.017
PMCID: PMC3229159

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The dCMP transferase activity of yeast Rev1 is biologically relevant during the bypass of endogenously generated AP sites.PMID 22024240Read ↗

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