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Article

DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase.

Journal of molecular biology - 11 Feb 2011

Nair Deepak T, Johnson Robert E, Prakash Louise, Prakash Satya, Aggarwal Aneel K

Abstract excerpt

Abasic (apurinic/apyrimidinic) sites are among the most abundant DNA lesions in humans, and they present a strong block to replication. They are also highly mutagenic because when replicative DNA polymerases manage to insert a nucleotide opposite the lesion, they prefer to insert an A. Rev1, a me...

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Source

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Identifiers

PMID: 21167175
DOI: 10.1016/j.jmb.2010.12.016
PMCID: PMC3127253

Genes

REV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21167175-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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