Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Virulence and Pathogenesis of HIV-1 Infection: An Evolutionary Perspective

20 Mar 2014

Abstract excerpt

Why some individuals develop AIDS rapidly whereas others remain healthy without treatment for many years remains a central question of HIV research. An evolutionary perspective reveals an apparent conflict between two levels of selection on the virus. On the one hand, there is rapid evolution of the virus in the host, and on the other, new observations indicate the existence of virus factors that affect the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Evolution and Genetic Dynamics
Share to HIV/AIDS Research and Interventions
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24653038
DOI: 10.1126/science.1243727

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Virulence and Pathogenesis of HIV-1 Infection: An Evolutionary PerspectivePMID 24653038Read ↗

The evolution of virulence in sexually transmitted HIV/AIDSSemantic proximity Read ↗

HIV pathogenesis: mechanisms of susceptibility and disease progression.Semantic proximity Read ↗

Evolution of mutation rate and virulence among human retroviruses.Semantic proximity Read ↗

Is the high virulence of HIV-1 an unfortunate coincidence of primate lentiviral evolution?Semantic proximity Read ↗

A Strong Case for Viral Genetic Factors in HIV VirulenceSemantic proximity Read ↗

Attenuation of HIV severity by slightly deleterious mutations can explain the long-term trajectory of virulence evolutionSemantic proximity Read ↗

Molecular pathogenesis of HIV-1.Semantic proximity Read ↗

The impact of HIV-1 within-host evolution on transmission dynamicsSemantic proximity Read ↗

The impact of HIV-1 within-host evolution on transmission dynamicsSemantic proximity Read ↗

Host genes and infectious diseases. HIV, other pathogens, and a public health perspective.Semantic proximity Read ↗

HIV pathogenesis: dynamics and genetics of viral populations and infected cells.Semantic proximity Read ↗

Understanding the mechanisms driving the spread of subtype C HIV-1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.