Article
Isolation and characterization of a Chinese hamster ovary cell line deficient in fatty alcohol:NAD+ oxidoreductase activity.
Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1990
James P F, Rizzo W B, Lee J, Zoeller R A
Abstract excerpt
We have isolated a mutant Chinese hamster ovary cell line that is defective in long-chain fatty alcohol oxidation. The ability of the mutant cells to convert labeled hexadecanol to the corresponding fatty acid in vivo was reduced to 5% of the parent strain. Whole-cell homogenates from the mutant...
Topics
- Alcohol Oxidoreductases
- Aldehyde Oxidoreductases
- Aldehydes
- Animals
- Biological Transport
- Cell Line
- Cricetinae
- Cricetulus
- Fatty Alcohols
- Female
- Kinetics
- Mutation
- Ovary
- Oxidation-Reduction
- Palmitic Acids