Article
Isolation and characterization of Chinese hamster ovary cell mutants defective in assembly of peroxisomes.
The Journal of cell biology - 1 Mar 1990
Tsukamoto T, Yokota S, Fujiki Y
Abstract excerpt
We made use of autoradiographic screening to isolate two Chinese hamster ovary (CHO) cell mutants deficient in peroxisomal dihydroxyacetonephosphate acyltransferase, a key enzyme for the biosynthesis of ether glycerolipids such as plasmalogens. Morphological analysis revealed no evidence of perox...
Topics
- Acetyl-CoA C-Acetyltransferase
- Acyltransferases
- Animals
- Cell Fusion
- Cell Line
- Cell Separation
- Cricetinae
- Cricetulus
- Fatty Acid Desaturases
- Female
- Hybrid Cells
- Microbodies
- Microscopy, Electron
- Mutation
- Ouabain
- Ovary
- Protein Biosynthesis
- RNA