Article
Mutants in a macrophage-like cell line are defective in plasmalogen biosynthesis, but contain functional peroxisomes.
The Journal of biological chemistry - 25 Apr 1992
Zoeller R A, Rangaswamy S, Herscovitz H, Rizzo W B, Hajra A K, Das A K, Moser H W, Moser A, Lazarow P B, Santos M J
Abstract excerpt
We have used a fluorescence-activated cytotoxicity protocol, 9-(1'-pyrene)nonanol (P9OH)/UV selection (Morand, O. H., Allen, L.-A. H., Zoeller, R. A., and Raetz, C. R. H. (1990) Biochim. Biophys. Acta 1034, 132-141), to isolate a series of plasmalogen-deficient mutants in a murine, macrophage-like cell line, RAW 264.7. Three of these mutants, RAW.7, RAW.12, and RAW.108, displayed varying degrees of plasmalogen...
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