Article
Mutants in a macrophage-like cell line are defective in plasmalogen biosynthesis, but contain functional peroxisomes.
The Journal of biological chemistry - 25 Apr 1992
Zoeller R A, Rangaswamy S, Herscovitz H, Rizzo W B, Hajra A K, Das A K, Moser H W, Moser A, Lazarow P B, Santos M J
Abstract excerpt
We have used a fluorescence-activated cytotoxicity protocol, 9-(1'-pyrene)nonanol (P9OH)/UV selection (Morand, O. H., Allen, L.-A. H., Zoeller, R. A., and Raetz, C. R. H. (1990) Biochim. Biophys. Acta 1034, 132-141), to isolate a series of plasmalogen-deficient mutants in a murine, macrophage-lik...
Topics
- Acyltransferases
- Animals
- CHO Cells
- Catalase
- Cell Line
- Cricetinae
- Fatty Alcohols
- Macrophages
- Mice
- Microbodies
- Microscopy, Fluorescence
- Mutation
