Article
Isolation and characterization of a gene affecting fatty acid elongation in Saccharomyces cerevisiae.
The Journal of biological chemistry - 2 Aug 1996
Toke D A, Martin C E
Abstract excerpt
Fatty acid elongation defective mutants were isolated from Saccharomyces cerevisiae by mutagenizing strains that were defective in fatty acid synthase (FAS) activity. Cells of the fatty acid synthase-defective strains can grow when supplemented with tetradecanoic acid (14:0) due to the presence of membrane bound elongation systems that can extend the 14 carbon fatty acid to longer chain species. After mutagenesis...
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