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Article

Fatty acid desaturation in an animal cell mutant defective in plasmanylethanolamine desaturase.

Biochimica et biophysica acta - 10 Feb 1994

Rangaswamy S, Zoeller R A

Abstract excerpt

We have recently reported the isolation of three plasmalogen-deficient mutants in a murine, macrophage-like cell line, RAW 264.7 (Zoeller et al. (1992) J. Biol. Chem. 267, 8299-8306). One of these mutant strains, RAW.12, is deficient in delta 1'-desaturase (plasmanylethanolamine desaturase, EC 1.14.99.19), the activity responsible for introducing the vinyl-ether double bond found in plasmalogens. We have examined...

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PMID: 8123685
DOI: 10.1016/0005-2760(94)90141-4

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