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Article

Atp8a1 deficiency is associated with phosphatidylserine externalization in hippocampus and delayed hippocampus-dependent learning.

Journal of neurochemistry - 1 Jan 2012

Levano Kelly, Punia Vineet, Raghunath Michael, Debata Priya Ranjan, Curcio Gina Marie, Mogha Amit, Purkayastha Sudarshana, McCloskey Dan, Fata Jimmie, Banerjee Probal

Abstract excerpt

The molecule responsible for the enzyme activity plasma membrane (PM) aminophospholipid translocase (APLT), which catalyzes phosphatidylserine (PS) translocation from the outer to the inner leaflet of the plasma membrane, is unknown in mammals. A Caenorhabditis elegans study has shown that ablation of transbilayer amphipath transporter-1 (TAT-1), which is an ortholog of a mammalian P-type ATPase, Atp8a1, causes...

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Identifiers

PMID: 22007859
DOI: 10.1111/j.1471-4159.2011.07543.x
PMCID: PMC3243772

Genes

TAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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