Article
C. elegans mitochondrial factor WAH-1 promotes phosphatidylserine externalization in apoptotic cells through phospholipid scramblase SCRM-1.
Nature cell biology - 1 May 2007
Wang Xiaochen, Wang Jin, Gengyo-Ando Keiko, Gu Lichuan, Sun Chun-Ling, Yang Chonglin, Shi Yong, Kobayashi Tetsuo, Shi Yigong, Mitani Shohei, Xie Xiao-Song, Xue Ding
Abstract excerpt
Externalization of phosphatidylserine, which is normally restricted to the inner leaflet of plasma membrane, is a hallmark of mammalian apoptosis. It is not known what activates and mediates the phosphatidylserine externalization process in apoptotic cells. Here, we report the development of an a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
