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Article

Perineurial Barrier Glia Physically Respond to Alcohol in an Akap200-Dependent Manner to Promote Tolerance.

Cell reports - 13 Feb 2018

Parkhurst Sarah J, Adhikari Pratik, Navarrete Jovana S, Legendre Arièle, Manansala Miguel, Wolf Fred W

Abstract excerpt

Ethanol is the most common drug of abuse. It exerts its behavioral effects by acting on widespread neural circuits; however, its impact on glial cells is less understood. We show that Drosophila perineurial glia are critical for ethanol tolerance, a simple form of behavioral plasticity. The perineurial glia form the continuous outer cellular layer of the blood-brain barrier and are the interface between the brain...

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Identifiers

PMID: 29444420
DOI: 10.1016/j.celrep.2018.01.049
PMCID: PMC5831198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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