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Article

Single molecule fluorescence study of the Bacillus thuringiensis toxin Cry1Aa reveals tetramerization.

The Journal of biological chemistry - 9 Dec 2011

Groulx Nicolas, McGuire Hugo, Laprade Raynald, Schwartz Jean-Louis, Blunck Rikard

Abstract excerpt

Pore-forming toxins constitute a class of potent virulence factors that attack their host membrane in a two- or three-step mechanism. After binding to the membrane, often aided by specific receptors, they form pores in the membrane. Pore formation either unfolds a cytolytic activity in itself or provides a pathway to introduce enzymes into the cells that act upon intracellular proteins. The elucidation of the...

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Identifiers

PMID: 22006922
DOI: 10.1074/jbc.M111.296103
PMCID: PMC3234970

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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