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Article

X-ray and Cryo-electron Microscopy Structures of Monalysin Pore-forming Toxin Reveal Multimerization of the Pro-form.

The Journal of biological chemistry - 22 May 2015

Leone Philippe, Bebeacua Cecilia, Opota Onya, Kellenberger Christine, Klaholz Bruno, Orlov Igor, Cambillau Christian, Lemaitre Bruno, Roussel Alain

Abstract excerpt

β-Barrel pore-forming toxins (β-PFT), a large family of bacterial toxins, are generally secreted as water-soluble monomers and can form oligomeric pores in membranes following proteolytic cleavage and interaction with cell surface receptors. Monalysin has been recently identified as a β-PFT that contributes to the virulence of Pseudomonas entomophila against Drosophila. It is secreted as a pro-protein that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25847242
DOI: 10.1074/jbc.M115.646109
PMCID: PMC4505573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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