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Article

Pancreatic ductal adenocarcinoma in hereditary diffuse gastric cancer. A case report.

Human pathology - 1 Mar 2012

Ottenhof Niki A, de Wilde Roeland F, Morsink Folkert H M, de Leng Wendy W J, Ausems Margreet G E M, Morreau Hans, van Hillegersberg Richard, Offerhaus G Johan A, Milne Anya N

Abstract excerpt

Hereditary diffuse gastric cancer is an autosomal dominant cancer syndrome characterized by highly penetrant diffuse gastric cancer. It is caused by germ line mutations in CDH1, encoding the cell-cell adhesion protein E-cadherin. Pancreatic ductal adenocarcinoma is one of the most dismal malignancies in humans. Although absent E-cadherin expression in pancreatic ductal adenocarcinoma is related to a higher tumor...

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Share to Adenocarcinoma
Share to Antigens, CD

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to DNA Mutational Analysis

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Share to Polymorphism, Single Nucleotide

Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins p21(ras)

Source

Identifiers

PMID: 21992816
DOI: 10.1016/j.humpath.2011.06.008

Genes

CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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