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Article

A meta-analysis of the prevalence of somatic mutations in the hMLH1 and hMSH2 genes in colorectal cancer.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland - 1 Mar 2012

Zhang R, Qin W, Xu G-L, Zeng F-F, Li C-X

Abstract excerpt

AIM: The study aimed to understand better the somatic mutations in the human MutL Homolog 1 (hMLH1) and human MutS Homolog 2 (hMSH2) genes in colorectal cancer (CRC) and to investigate the differences derived from ethnicity, family history, detection method and microsatellite instability (MSI). METHOD: The terms 'hMSH2' or 'hMLH1' and 'colorectal cancer' 'colorectal carcinoma' or 'colorectal tumour' were searched...

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Identifiers

PMID: 21988782
DOI: 10.1111/j.1463-1318.2011.02858.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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