Article
Mutation analysis of hMSH2 and hMLH1 in colorectal cancer patients in India.
Genetic testing - 1 Jan 2004
Rajkumar Thangarajan, Soumittra Nagasamy, Pandey Durgatosh, Nancy Karunakaran Nirmala, Mahajan Vikas, Majhi Urmila
Abstract excerpt
The aim of this work was to study the mutation profile in hMSH2 and hMLH1 genes in hereditary nonpolyposis colorectal cancer (HNPCC) patients in India. On the basis of the Bethesda criteria, 31 colorectal cancer patients were studied first for microsatellite instability, using the five markers re...
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