Article

Rare single‐nucleotide variants of MLH1 and MSH2 genes in patients with Lynch syndrome

2023-06-01

Abstract excerpt

Approximately 5% of colorectal cancers (CRCs) are hereditary. Lynch syndrome (LS), also known as hereditary nonpolyposis colorectal cancer (HNPCC), is the most common form of recognized hereditary CRC. Although Iran, a developing country, has a high incidence of CRC, the spectrum of mutations has yet to be thoroughly investigated. Therefore, this study aimed to investigate pathogenic and non-pathogenic variants in...

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Literature Corpus work: 08a422e5-ace5-5858-9aaa-fb2c0abb3bd5
DOI: 10.22541/au.168559926.65085043/v1

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