Role of the purine repressor hinge sequence in repressor function.

doi:10.1128/jb.176.6.1767-1772.1994

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Article

Role of the purine repressor hinge sequence in repressor function.

Journal of bacteriology - 1 Mar 1994

Choi K Y, Zalkin H

Abstract excerpt

A protease-hypersensitive hinge sequence in Escherichia coli purine repressor (PurR) connects an N-terminal DNA-binding domain with a contiguous corepressor-binding domain. Binding of one molecule of dimeric repressor to operator DNA protects the hinge against proteolytic cleavage. Mutations in t...

Topics

Amino Acid Sequence
Bacterial Proteins
DNA-Binding Proteins
Escherichia coli
Escherichia coli Proteins
Models, Genetic
Molecular Sequence Data
Mutation
Repressor Proteins

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