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Article

Association between immune cell attributes, serum metabolites, inflammatory protein factors, and colorectal cancer: A Mendelian randomization study.

Medicine - 29 Nov 2024

Zhang Jingting, Chen Hongyao, Yang Renyi, Tang Jincheng, Yu Xiaopeng, Zeng Puhua, Peng Wei

Abstract excerpt

Understanding the role of the tumor microenvironment in colorectal cancer (CRC) progression remains a challenge due to its complexity. Investigating the interplay between immune cell characteristics, serum metabolites, inflammatory protein factors, and CRC could unveil novel therapeutic avenues. We used 2-sample Mendelian randomization (MR) on Genome-Wide Association Studies (GWAS) data to explore causal links...

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Colorectal Neoplasms
Genome-Wide Association Study
Mendelian Randomization Analysis
Polymorphism, Single Nucleotide
Risk Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Microenvironment

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PMID: 39612465
DOI: 10.1097/MD.0000000000040691
PMCID: PMC11608676

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