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Article

CHL-1 provides an essential function affecting cell proliferation and chromosome stability in Caenorhabditis elegans.

DNA repair - 10 Nov 2011

Chung George, O'Neil Nigel J, Rose Ann M

Abstract excerpt

A family of helicases that are important in maintaining genome stability is the iron-sulfur group. Members of this family include DOG-1/FANCJ, RTEL1, XPD and Chl1p/DDX11. In Caenorhabitis elegans, the predicted gene M03C11.2 has orthology to the CHL1 (Chromosome loss 1) gene in Saccharomyces cerevisiae and DDX11 (DEAD/H box polypeptide 11) in humans. In this paper, we show that the chl-1 gene in C. elegans is...

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Identifiers

PMID: 21968058
DOI: 10.1016/j.dnarep.2011.09.011

Genes

DDX11
CHL1
RTEL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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