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Article

A genome-wide survey and systematic RNAi-based characterization of helicase-like genes in Caenorhabditis elegans.

DNA research : an international journal for rapid publication of reports on genes and genomes - 31 Aug 2007

Eki Toshihiko, Ishihara Takeshi, Katsura Isao, Hanaoka Fumio

Abstract excerpt

Helicase-like proteins play a crucial role in nucleic acid- and chromatin-mediated reactions. In this study, we identified 134 helicase-like proteins in the nematode Caenorhabditis elegans and classified the proteins into 10 known subfamilies and a group of orphan genes on the basis of sequence similarity. We characterized loss-of-function phenotypes in RNA interference (RNAi)-treated animals for helicase family...

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Identifiers

PMID: 17921522
DOI: 10.1093/dnares/dsm016
PMCID: PMC2533593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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