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Article

Cells derived from young bone marrow alleviate renal aging.

Journal of the American Society of Nephrology : JASN - 1 Nov 2011

Yang Hai-Chun, Rossini Michele, Ma Li-Jun, Zuo Yiqin, Ma Ji, Fogo Agnes B

Abstract excerpt

Bone marrow-derived stem cells may modulate renal injury, but the effects may depend on the age of the stem cells. Here we investigated whether bone marrow from young mice attenuates renal aging in old mice. We radiated female 12-mo-old 129SvJ mice and reconstituted them with bone marrow cells (BMC) from either 8-wk-old (young-to-old) or 12-mo-old (old-to-old) male mice. Transfer of young BMC resulted in markedly...

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Identifiers

PMID: 21965376
DOI: 10.1681/ASN.2010090982
PMCID: PMC3231782

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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