Article
Aging and senescence-associated analysis of the aged kidney glomerulus highlights the role of mesangial cells in renal aging
2023-08-12
Abstract excerpt
Most causes of chronic kidney disease begin with injury to the glomerulus and involve progressive loss of kidney function. The glomerulus is a capillary bed where blood filtration to produce urine in the kidney occurs. During aging, there is progressive loss of glomeruli and filtration capacity of the kidney because podocytes, the glomerular epithelial cell, are lost with aging and after injury. Podocytes cannot d...
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Identifiers and source
- Literature Corpus work
- f03d5dbf-f502-546c-b4aa-66262e13eb19
- DOI
- 10.1101/2023.08.10.552883