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Transplantation of mesenchymal stem cells from young donors delays aging in mice

18 Aug 2011

Abstract excerpt

Increasing evidence suggests that the loss of functional stem cells may be important in the aging process. Our experiments were originally aimed at testing the idea that, in the specific case of age-related osteoporosis, declining function of osteogenic precursor cells might be at least partially responsible. To test this, aging female mice were transplanted with mesenchymal stem cells from aged or young male...

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PMID: 22355586
DOI: 10.1038/srep00067

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