Article
Association between suicide attempt and a tri-allelic functional polymorphism in serotonin transporter gene promoter in Chinese patients with schizophrenia.
Neuroscience letters - 31 Oct 2011
Hung Chi-Fa, Lung For-Wey, Chen Chien-Hsiun, O'Nions Elizabeth, Hung Tai-Hsin, Chong Mian-Yoon, Wu Ching-Kuan, Wen Jung-Kwang, Lin Pao-Yen
Abstract excerpt
Mounting evidence supports the association between a polymorphism in the serotonin transporter gene promoter region (5-HTTLPR) and suicidal behaviour. Recently, a novel variant of the 5-HTTLPR L allele was identified. The previously unknown L(G) allele produced similar levels of gene expression to the S allele and might have been misclassified as a "high-expression" allele in previous association studies. In this...
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