Article
Association between violent suicidal behavior and the low activity allele of the serotonin transporter gene.
Molecular psychiatry - 1 May 2001
Courtet P, Baud P, Abbar M, Boulenger J P, Castelnau D, Mouthon D, Malafosse A, Buresi C
Abstract excerpt
There is compelling evidence that serotonin system dysfunction is associated with certain behavioral disorders, such as suicidal behavior and impulsive aggression. A functional polymorphism in the promoter region of the serotonin transporter gene (5-HTTLPR) was recently identified and the presence of the short allele found to be associated with a lower level of expression of the gene, lower levels of 5-HT uptake,...
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