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Article

The influence of the serotonin transporter gene 5-HTTLPR polymorphism on suicidal behaviors: a meta-analysis.

Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2019

Fanelli Giuseppe, Serretti Alessandro

Abstract excerpt

Suicidal Behavior (SB) is the second leading cause of death among youths worldwide and the tenth among all age groups. Inherited genetic differences have a role in suicidality with heritability ranging from 30 to 55%. The SLC6A4 5-HTTLPR gene variant has been largely investigated for association with SB, with controversial results. In this work, we sought to determine whether the results of previous meta-analyses...

Topics

Alleles
Gene Frequency
Humans
Polymorphism, Genetic
Serotonin Plasma Membrane Transport Proteins
Suicide

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 30125622
DOI: 10.1016/j.pnpbp.2018.08.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-30125622-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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