Familial suicide behaviour: association with probands suicide attempt characteristics and 5-HTTLPR polymorphism.

doi:10.1111/j.1600-0447.2004.00340.x

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Article

Familial suicide behaviour: association with probands suicide attempt characteristics and 5-HTTLPR polymorphism.

Acta psychiatrica Scandinavica - 1 Dec 2004

Correa H, Campi-Azevedo A C, De Marco L, Boson W, Viana M M, Guimarães M M, Costa E, Miranda D M, Romano-Silva M A

Abstract excerpt

OBJECTIVE: There is compelling evidence that a serotonergic dysfunction may play a major role in suicide behaviour and it has also been demonstrated that suicide is, at least partially, genetically determined. Thus, the serotonin-related genes are the major candidates. Previously a functional polymorphism in the promoter region of the serotonin transporter gene (5-HTTLPR) was identified and the presence of the...

Topics

Behavior
Brazil
Depressive Disorder
Family
Genetic Predisposition to Disease
Genotype
Humans
Polymorphism, Genetic
Receptor, Serotonin, 5-HT1A
Schizophrenia
Serotonin
Suicide, Attempted

Source

Open in PubMed

Identifiers

PMID: 15521831
DOI: 10.1111/j.1600-0447.2004.00340.x

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