Article
Male-specific association between the 5-HTTLPR S allele and suicide attempts in alcohol-dependent subjects.
Journal of psychiatric research - 1 Mar 2005
Limosin Frédéric, Loze Jean-Yves, Boni Claudette, Hamon Michel, Adès Jean, Rouillon Frédéric, Gorwood Philip
Abstract excerpt
Changes in serotoninergic neurotransmission have been implicated in the pathogenesis of suicidal behavior and alcohol dependence. Previous studies have demonstrated an association between suicide attempts and the 5-HTTLPR S allele in alcohol-dependent subjects. We investigated the frequency of the S allele of 5-HTTLPR in a sample of 100 French Caucasian alcohol-dependent inpatients (48 men and 52 women) with and...
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