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Article

Role of the Ha-ras (RasH) oncogene in mediating progression of the tumor cell phenotype (review).

Anticancer research - 1 Jan 2000

Boylan J F, Jackson J, Steiner M R, Shih T Y, Duigou G J, Roszman T, Fisher P B, Zimmer S G

Abstract excerpt

Recent experimental evidence indicates that the c-Ha-ras (rasH) oncogene may be causally involved in the etiology and evolution of specific human neoplasms. In addition, cultured cells transformed by the rasH oncogene can induce both a tumorigenic and a metastatic phenotype when expressed in appropriate cultured cells. To begin to define the molecular and biochemical mechanism(s) by which the rasH oncogene induce...

Topics

Animals
Cell Line
Cell Transformation, Neoplastic
Genes, ras
Humans
Neoplasms
Phenotype

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2195986

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2195986-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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