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Predicting Progression to Advanced Age-Related Macular Degeneration from Clinical, Genetic, and Lifestyle Factors Using Machine Learning.

Ophthalmology - 1 Apr 2021

Ajana Soufiane, Cougnard-Grégoire Audrey, Colijn Johanna M, Merle Bénédicte M J, Verzijden Timo, de Jong Paulus T V M, Hofman Albert, Vingerling Johannes R, Hejblum Boris P, Korobelnik Jean-François, Meester-Smoor Magda A, Ueffing Marius, Jacqmin-Gadda Hélène, Klaver Caroline C W, Delcourt Cécile

Abstract excerpt

PURPOSE: Current prediction models for advanced age-related macular degeneration (AMD) are based on a restrictive set of risk factors. The objective of this study was to develop a comprehensive prediction model applying a machine learning algorithm allowing selection of the most predictive risk factors automatically. DESIGN: Two population-based cohort studies. PARTICIPANTS: The Rotterdam Study I (RS-I; training...

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PMID: 32890546
DOI: 10.1016/j.ophtha.2020.08.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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