Article
Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents.
Mutation research - 1 Jul 1990
Beranek D T
Abstract excerpt
Alkylating agents, because of their ability to react directly with DNA either in vitro or in vivo, or following metabolic activation as in the case of the dialkylnitrosamines, have been used extensively in studying the mechanisms of mutagenicity and carcinogenicity. Their occurrence is widespread...
Topics
- Alkylating Agents
- Alkylation
- Animals
- Carcinogenicity Tests
- DNA
- Humans
- Methylation
- Mutagenicity Tests
- Mutation