Sequence-dependent formation of alkyl DNA adducts: a review of methods, results, and biological correlates.

doi:10.1016/0027-5107(90)90157-y

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Article

Sequence-dependent formation of alkyl DNA adducts: a review of methods, results, and biological correlates.

Mutation research - 1 Jan 2000

Richardson F C, Richardson K K

Abstract excerpt

Understanding the influence of the DNA sequence on chemical-DNA interactions may provide insight into the processes of chemical carcinogenesis and mutagenesis. This article provides a brief overview of studies and methods devoted to examining the distribution of DNA adducts produced by alkylating...

Topics

Alkylating Agents
Alkylation
Base Sequence
DNA
DNA Damage
Molecular Sequence Data
Mutation

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