Article
Genetics of sputum gene expression in chronic obstructive pulmonary disease.
PloS one - 1 Jan 2011
Qiu Weiliang, Cho Michael H, Riley John H, Anderson Wayne H, Singh Dave, Bakke Per, Gulsvik Amund, Litonjua Augusto A, Lomas David A, Crapo James D, Beaty Terri H, Celli Bartolome R, Rennard Stephen, Tal-Singer Ruth, Fox Steven M, Silverman Edwin K, Hersh Craig P
Abstract excerpt
Previous expression quantitative trait loci (eQTL) studies have performed genetic association studies for gene expression, but most of these studies examined lymphoblastoid cell lines from non-diseased individuals. We examined the genetics of gene expression in a relevant disease tissue from chronic obstructive pulmonary disease (COPD) patients to identify functional effects of known susceptibility genes and to...
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