Article
Ki-ras proto-oncogene mutations in sporadic colorectal adenomas: relationship to histologic and clinical characteristics.
Gastroenterology - 1 Aug 2001
Maltzman T, Knoll K, Martinez M E, Byers T, Stevens B R, Marshall J R, Reid M E, Einspahr J, Hart N, Bhattacharyya A K, Kramer C B, Sampliner R, Alberts D S, Ahnen D J
Abstract excerpt
BACKGROUND & AIMS: [corrected] The goal of this study was to examine the relationship between Ki-ras mutations in colorectal adenomas and characteristics of both the subject (age, gender, and family/personal history of colonic neoplasia) and the adenoma (multiplicity, size, location, and histologic features). METHODS: Ki-ras mutations were detected by direct sequencing in 738 adenomatous polyps removed at...
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