Article
Associations between dietary intake and Ki-ras mutations in colon tumors: a population-based study.
Cancer research - 15 Dec 2000
Slattery M L, Curtin K, Anderson K, Ma K N, Edwards S, Leppert M, Potter J, Schaffer D, Samowitz W S
Abstract excerpt
Ki-ras mutations are thought to be early events in the carcinogenic process leading to colon tumors. Dietary factors associated with colon cancer may be associated with these mutations. Data from a population-based, multicenter, case-control study of colon cancer were used to determine whether dietary factors are associated with Ki-ras mutations. Ki-ras mutations were detected by direct sequencing of codons 12...
Topics
- Adult
- Aged
- Case-Control Studies
- Codon
- Colonic Neoplasms
- DNA Methylation
- Diet
- Exons
- Folic Acid
- Genes, ras
- Humans
- Middle Aged
