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Article

Protease-activated receptor-2 modulates protease-activated receptor-1-driven neointimal hyperplasia.

Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2011

Sevigny Leila M, Austin Karyn M, Zhang Ping, Kasuda Shogo, Koukos Georgios, Sharifi Sheida, Covic Lidija, Kuliopulos Athan

Abstract excerpt

OBJECTIVE: Emerging evidence suggests that protease-activated receptors-1 and -2 (PAR1 and PAR2) can signal together in response to proteases found in the rapidly changing microenvironment of damaged blood vessels. However, it is unknown whether PAR1 and PAR2 promote or mitigate the hyperplastic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21940952
DOI: 10.1161/ATVBAHA.111.238261
PMCID: PMC3241440

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21940952-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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