Article
Circulating PCSK9 in patients with type 2 diabetes and related metabolic disorders.
Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis - 1 Jan 2000
Ibarretxe Daiana, Girona Josefa, Plana Núria, Cabré Anna, Ferré Raimón, Amigó Núria, Guaita Sandra, Mallol Roger, Heras Mercedes, Masana Luis
Abstract excerpt
BACKGROUND: PCSK9 is a pivotal molecule in the regulation of lipid metabolism. Previous studies have suggested that PCSK9 expression and its function in LDL receptor regulation could be altered in the context of diabetes. The aim was to assess PCSK9 plasma levels in patients with type 2 diabetes (T2DM) and other related metabolic disorders as well as its relation to the metabolomic profile generated by nuclear...
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