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Article

The application of molecular diagnostic studies interrogating EGFR and KRAS mutations to stained cytologic smears of lung carcinoma.

American journal of clinical pathology - 1 Oct 2011

Betz Bryan L, Roh Michael H, Weigelin Helmut C, Placido Jeremiah B, Schmidt Lindsay A, Farmen Sara, Arenberg Doug A, Kalemkerian Gregory P, Knoepp Stewart M

Abstract excerpt

EGFR and KRAS mutation analyses are of increasing importance for guiding the treatment of non-small cell lung carcinomas. Insufficient cellularity of cell blocks can represent an impediment to the performance of these tests. We investigated the usefulness of cytologic direct smears as an alternative specimen source for mutation testing. Tumor cell-enriched areas from freshly prepared and archived rapid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21917678
DOI: 10.1309/AJCP84TUTQOSUONG

Genes

EGFR
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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