Article
Detection of epidermal growth factor receptor mutation in non-small-cell lung carcinoma using cytological and histological specimens.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000
Xu Haimiao, Sun Wenyong, Zhang Gu, Cheng Yue
Abstract excerpt
PURPOSE: Epidermal growth factor receptor (EGFR) mutations are prerequisites for the targeted therapy with anti-EGFR tyrosine kinase inhibitors (TKIs) in non-small-cell lung carcinomas (NSCLCs). In patients with advanced-stage NSCLC, sometimes cytological specimens, including those from fine-needle aspiration cytology (FNAC) and pleural effusion, are the only materials for mutation analysis. The purpose of this...
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