Article
Epidermal growth factor receptor gene analysis with a highly sensitive molecular assay in routine cytologic specimens of lung adenocarcinoma.
American journal of clinical pathology - 1 Sept 2012
Allegrini Sara, Antona Jlenia, Mezzapelle Rosanna, Miglio Umberto, Paganotti Alessia, Veggiani Claudia, Frattini Milo, Monga Guido, Balbo Piero, Boldorini Renzo
Abstract excerpt
Epidermal growth factor receptor (EGFR) gene mutational analysis is critical for guiding the treatment of lung adenocarcinoma. In everyday clinical practice, EGFR testing is frequently centralized in referral laboratories that may receive paucicellular cytologic specimens, often fixed in various ways. We conducted a search for EGFR mutations in 108 cytologic samples of lung adenocarcinoma from different hospitals...
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