Article
Identification of EGFR mutation, KRAS mutation, and ALK gene rearrangement in cytological specimens of primary and metastatic lung adenocarcinoma.
Cancer cytopathology - 1 Sept 2013
Cai Guoping, Wong Rebecca, Chhieng David, Levy Gillian H, Gettinger Scott N, Herbst Roy S, Puchalski Jonathan T, Homer Robert J, Hui Pei
Abstract excerpt
BACKGROUND: The identification of molecular alterations has an important therapeutic implication in patients with lung adenocarcinomas. In the current study, the authors evaluated their experience with the identification of epidermal growth factor receptor (EGFR), Kirsten rat sarcoma viral oncogene homolog (KRAS) mutation, and anaplastic lymphoma kinase (ALK) gene rearrangement using cytological specimens of...
Topics
- Adenocarcinoma
- Adult
- Aged
- Aged, 80 and over
- Anaplastic Lymphoma Kinase
- Biomarkers, Tumor
- Bone Neoplasms
- Cytodiagnosis
- DNA, Neoplasm
- ErbB Receptors