Article
EGFR and KRAS mutational profiling in fresh non-small cell lung cancer (NSCLC) cells.
Journal of cancer research and clinical oncology - 1 Aug 2013
Stella Giulia M, Scabini Roberta, Inghilleri Simona, Cemmi Francesca, Corso Simona, Pozzi Ernesto, Morbini Patrizia, Valentini Adele, Dore Roberto, Ferrari Simona, Luisetti Maurizio, Zorzetto Michele
Abstract excerpt
PURPOSE: Knowledge of tumor mutational status has become a priority for effective NSCLC-tailored treatment. NSCLC diagnosis is more often reached through biopsy; thus, there is a clear need to implement for routine tumor molecular profiling on small cytological samples. This work aims to screen and compare the EGFR and KRAS mutational prevalence in fresh tumor cells and in corresponding routinely processed...
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